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Objective To investigate the types of common chronic diseases and common drugs in the elderly visiting primary medical institutions in China.Methods Cluster sampling was adopted in eight provinces/cities/autonomous region of Zhejiang,Jilin,Henan,Shanghai,Chongqing,Gansu,Guangxi and Jiangsu.Sampling sites were selected and information was collected through the online reporting system of common diseases and drug costs of the elderly in primary hospitals at all levels in China.On these grounds,the basic situation of primary medical institutions,the common chronic diseases and common drugs for people aged 65 years and above were investigated.Results Primary hypertension(65.7％ or 46/70)and arthropathy(10.0％ or 7/70)were the most common chronic diseases in the elderly visiting primary medical institutions.The consultation rate of primary hypertension was highest both in rural areas(58.3％,i.e.the ratio of 21 over 36 primary medical institutions)and in urban areas(73.5％,i.e.the ratio of 25 over 34 primary medical institutions).The primary medical institutions with consultation rates of hypercholesterolemia/hyperlipidemia (x2 =5.137,P=0.023),diabetes(x2 =3.868,P =0.049)and dyspepsia(Fisher's exact test,P =0.026)as the top 3 chronic diseases were more often seen in urban areas than in rural areas,while the primary medical institutions with consultation rates of cerebrovascular diseases as the top 3 chronic diseases were more often seen in the rural areas than in urban areas(x2=9.974,P =0.002).More primary medical institutions with consultation rates of benign prostatic hyperplasia and primary osteoporosis as the top 10 chronic diseases were found in urban areas than in rural areas(x2 =4.054 and 3.861,P =0.044 and 0.049,respectively),while more primary medical institutions with consultation rates of heart failure as the top 10 chronic diseases were found in rural areas than in urban areas(x2 =3.865,P =0.049).Aspirin,nifedipine and simvastatin one by one were most commonly used in people aged 65 years and over in primary medical institutions.Conclusions Primary hypertension is the most common chronic disease among the elderly visiting primary medical institutions in both rural and urban.Common chronic diseases in primary medical institutions are different between the urban and rural areas.Regional differences and urban-rural differences should be taken into account in drug preparation.There are some irregularities in the use of drugs and insufficient stocks of essential drugs in basic-level medical institutions.
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Objective To investigate the relationship between frailty and serum biomarkers in the elderly. Methods A total of 371 elderly individuals aged 60 years and above with complete medical data were recruited during health examinations. Frailty phenotype assessment and comprehensive geriatric assessment were conducted.Serum levels of interleukin-6 (IL-6 ) ,high sensitivity C-reactive protein(hs-CRP) ,tumor necrosis factor-α(TNF-α) ,homocysteine(Hcy) ,insulin-like growth factor-1(IGF-1) ,25-hydroxyvitamin D[25(OH)D] ,folic acid and vitamin B12(VitB12) were detected by enzyme-linked immunosorbent assays ( ELISA ) and chemiluminescence immunoassays. Associations between frailty and the above factors were analyzed. Results Serum levels of IL-6 ,TNF-α ,Hcy and IGF-1 were significantly elevated along with progressive increase in frailty severity(all P＜0.05).There were a downward trend in serum 25(OH)D levels and an upward trend in serum hs-CRP ,folic acid and VitB12 levels as frailty severity increased ,but the changes did not amount to any statistical significance(all P＞0.05).Logistic regression analysis showed that ,after adjusting for age ,gender ,body mass index (BMI)and some clinical aspects (hearing loss ,urinary incontinence ,pain ,malnutrition ,cognitive dysfunction ,decreased activities of daily living ,depression , insomnia ,and anemia) ,serum levels of IL-6(OR=1.012 ,95% CI=1.005-2.041 ,P=0.033) ,IGF-1 (OR= 1.017 ,95% CI = 1.011-1.118 ,P= 0.021)and Hcy (OR= 1.007 ,95% CI :1.002-1.073 ,P=0.047)were significantly associated with frailty status. Conclusions Serum levels of IL-6 ,Hcy and IGF-1 are related to frailty status and may be used as potential biomarkers for the assessment of frailty in older adults.
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Frailty is a geriatric syndrome that has been implicated as a causative and prognostic factor for cardiovascular disease (CVD).Frailty and CVD are often concurrent and mutually promotive.The prevalence of frailty ranges from 10％ to 60％ in patients with CVD,depending on different tools and cutoffs chosen to define frailty.Short-and long-term prognosis of CVD are both affected by frailty.The presence of frailty is correlated with an increase in complications,outpatient and emergency department visits,hospital admissions and stays,and mortality in patients with CVD.Early prevention and clinical intervention can delay or even reverse the development of frailty,thus improving the prognosis for CVD.
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With the aging of the global population,frailty is now considered a unique old age syndrome,has become an important worldwide public health problems.The elderly people is at increased risk of falls,hip fractures,disability,death and other risks.Motor system disease as an independent risk factor participates in frailty progress and interacts with each other.This article reviews recent studies on frailty and motor system diseases.
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Objective To explore the relationship between the severity of frailty and muscle mass/function in older people,and to determine whether and/or how the results would be influenced by the assessment method for frailty.Methods A total of 106 older adults aged 63-95 years were recruited from individuals undergoing regular health examinations at the Outpatient Department of Beijing Hospital.The characteristics of participants were collected through a questionnaire and subsequently evaluated.Frailty was assessed by both the Fried phenotype and an index of accumulated deficits (FI).Sarcopenia was identified based on the criteria of the Asian Working Group for Sarcopenia (AWGS).Average skeletal muscle mass,appendicular skeletal muscle mass and the appendicular skeletal muscle index (ASMI) were measured by bioelectrical impedance analysis (BIA).Furthermore,grip strength,the 4 m walking test,the timed up and go test (TUGT),the five times sit to stand test (FTSST),and the balance test were performed to investigate the physical performance.Results There were 15 (14.2％) frail and 65 (61.3％) pre-frail cases in this group.Poor grip strength 59 (55.7％) and slow gait speed 33 (31.1％) were more prevalent in frail older people.Meanwhile,when the phenotypic definition of frailty was used,muscle mass and ASMI decreased as the severity of frailty increased (F=6.579,3.969,4.507,respectively;all P＜0.05).Frail older people had significantly slower gait speed and poorer grip strength than those who were not frail (F=23.897,4.583,respectively;both P＜0.05).Moreover,frail older people were more likely to be sarcopenia (53.5％) than those who were pre frail (30.8％) or not frail (3.8％).Participants with frailty performed worse on FTSST,TUGT and the balance test (all P＜0.05) and had markedly lower levels of FI (0.15±0.04,0.18±0.06,and 0.28±0.09,respectively;F=21.764,P＜0.05) than those in the pre-frail and non-frail groups.Appendicular skeletal muscle mass,skeletal muscle mass,grip strength and walking speed were negatively correlated with FI (r =-0.256,-0.321,-0.343,-0.374,respectively;all P＜0.05) while ASMI showed no statistical correlation with FI (P＞0.05).Conclusions Poor grip strength and slow gait speed are very common in frail older people.There is a close correlation between muscle mass/function and frailty.The degree of association of frailty severity with physical performance remains largely unchanged regardless of what assessment method is used.
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Objective To analyze the literature distribution and research status of benign prostatic hyperplasia (BPH) in the elderly published in Chinese Medical Association journals.Methods The literatures of elderly BPH published in 88 kinds of Chinese Medical Association journals from 2009 to 2013 were collected.The publication year,distribution,content,author,institution and region of these literatures were analyzed.Results From 2009 to 2013,203 articles about elderly BPH were published in 10 kinds of journals.These literatures were published mostly in 2013 (50 articles,24.6％),secondly in 2010 (46 articles,22.7％) and 2009 (43 articles,21.2％),which were mostly published in Chinese Journal of Geriatrics (87 articles,42.9 ％).Most researches were focused on the fields of clinical treatment of BPH in the elderly,etiology,cross-sectional investigation and perioperative nursing,while the progresses in pathophysiology and diagnosis were relatively small,and the most published form was treatise (166 articles,81.8％).Authors who published the most articles were Yang Yong from Department of Urology Surgery in PLA General Hospital and Zhang Xianghua from Department of Urology Surgery in Peking University First Hospital (both,4 articles,3.5 ％),the institutions which published the most articles were Beijing Hospital and Beijing Chaoyang Hospital (both,9 articles,4.4 ％),and the provinces or cities which published the most articles were Beijing (75 articles,36.9％),Shanghai and Zhejiang (both,17 articles,8.4％) and Hunan (16 articles,7.9％).Among the 203 articles,35 articles (17.2％) were supported by founds.Conclusions Chinese Medical Association journals are the important sonrce to acquire literatures on elderly BPH for medical workers.The distribution of journals is relatively concentrated,but the distribution of author,institution and region in these articles is dispersed.Studies on clinical treatment of elderly BPH,etiology,inventory survey and perioperative nursing are especially concerned within nearly 5 years.
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Objective To analyze the literature distribution and research status of osteoporosis in the elderly published in Chinese Medical Association journals.Methods The literatures of elderly osteoporosis published in Chinese Medical Association journals from 2008 to 2013 were collected.And the publication year,distribution,content,institution and region of the literatures were analyzed.Results From 2008 to 2013,there were 76 articles about osteoporosis in the elderly published in 22 kinds of journals of the Chinese Medical Association.Among these journals,the Chinese Journal of Geriatrics-published elderly osteoporosis articles occupied the most number [28 (36.8％)].There were 21 articles published mostly in 2013 (27.6％),secondly in 2009 (17 articles,22.4％) and 2012 (12 articles,15.8％).The province or city that published more than 10 articles was Beijing (18 articles,23.7％),Zhejiang (13 articles,17.1％),Shanghai (10 articles,13.2％) and Guangdong (10 articles,13.2％).The institution that published most articles was Beijing Jishuitan Hospital (4articles,5.3％).The main contents of these literatures included the influencing factors,diagnosis,treatment strategy,bone metabolism and surgery treatment for elderly osteoporosis.Conclusions Chinese Medical Association journals are the important source to acquire osteoporosis literature for the medical workers.The distribution of journal is relatively concentrated,but the distribution of authors,institution is dispersed.Chinese Journal of Geriatrics publishes the most number of articles.The research of osteoporosis has attracted more attention.
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Objective To analyze the citation characteristics of literatures in Chinese Journal of Geriatrics published from 2008 to 2012.Methods According to the information from Wanfang database,articles in Chinese Journal of Geriatrics published from 2008 to 2012 were surveyed.The quantity,type of languages and the self-cited rate,etc were analyzed,and the Price's index,half life of literatures were calculated.Results Of the 1567 papers published in the journal from 2008 to 2012,1479 papers cited 16054 literatures,with a citation rate of 94.4％.The average number of citations in each paper was 10.25.The major language of citation was English (73.33％),followed by Chinese (26.67％),and only one citation was in Japanese.The self cited rates of author and periodical were 1.20％ and 5.23％,respectively.The Price's index was 45.71％ and the half-life of literatures was 4.27 years.Conclusions The authors of Chinese Journal of Geriatrics cite a wide range of literature,and the journal plays an important role in publicizing research achievements of geriatric medicine.However,the average number of citations in each paper,timeliness and novelty of cited literatures,diversity of citation languages need further improving.
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Objective To study the literatures distribution and research status of the elderly tuberculosis published in the Chinese Medical Association Journals (CMAJ) from 2004-2013 in order to provide literature methodological data for the tuberculosis research.Methods The literatures on the elderly tuberculosis published in 82 kinds of CMAJs from 2004-2013 were classified and analyzed.The publication year,distribution,content,author,institution and region of these literatures were analyzed.Results There were 66 articles about the elderly tuberculosis published in 20 kinds of the Chinese Medical Association Journals.These literatures were published mostly in 2011 (16 articles,24.2％),secondly in 2012 (13 articles,19.6％) and 2010 (7 articles,10.6％),which were published mostly in Chinese Journal of Geriatrics (15 articles,22.7％).The main contents included clinical diagnosis and treatment,epidemiological investigation and drug research.The most published form was treatise (55 articles,83.3 ％).Most of the articles involved in pulmonary tuberculosis (34 articles,51.6 ％).The provinces or cities in which the most articles were published were Beijing (28 articles,42.4％) and Shandong (6 articles,9.1％).There was significantly difference in the article number between 2004-2008 and 2009-2013 (P＜ 0.05).The epidemiology,drug resistance mechanism,influencing factors,clinical characteristics,diagnosis and treatment strategy of the elderly tuberculosis,especially diagnosis and treatment development were well discussed in these literatures.Conclusions The literatures of the elderly tuberculosis published in Chinese Medical Association Journals are insufficient in quantity,with number increases of articles significantly over the past 5 years.Projects supported by the foundation is less and discipline construction should be strengthened.The distributions of authors and the primary population of tuberculosis are different,and early diagnosis and treatment of pulmonary tuberculosis in the elderly are concerned especially.
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Objective To analyze the articles published in Chinese Journal of Geriatrics from 2008 to 2012 so as to understand the characteristics of published papers and research progress in geriatric medicine.Methods Based on Wanfang database,bibliometric analysis was conducted to analyze the quantity,types,authors,affiliations,fund support of all the articles published from 2008 to 2012 in Chinese Journal of Geriatrics.Results A total of 1567 papers were published in the journal from 2008 to 2012.The column with the most published papers was clinical research (1008 papers,64.3 ％),followed by experimental researches,reviews and lectures,investigations etc.The discipline with the most articles published in the journal was cardiovascular medicine,followed by surgery,neurology; respiratory etc.1356 authors from 506 affiliations published paper as the first author in the journal during this five years,with the maximal number being 7 papers and the major affiliation being affiliated hospitals of medical colleges (733 papers,49.3 ％).Authors from Beijing,Zhejiang,Jiangsu,Shanghai published more papers than those from other provinces.29.0％ (455papers) of the total papers were supported by fund,among which the majority was provincial fund,followed by national fund,municipal fund,ministry fund and military fund.Conclusions A relatively stable core author group has formed for Chinese Journal of Geriatrics,and the articles are of high quality.Chinese Journal of Geriatrics is one of the highest academic journals in geriatric medicine.
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Objective To analyze the structural,content and language characteristics of English abstract in domestic versus international geriatrics journals in order to promote international exchange in geriatric medicine research in our country.Methods In this paper,we analyzed the characteristics and contents of original articles published in 5 foreign journals (IF＞3.0) from Pubmed database (n=60) and 5 core (the source of statistics) domestic geriatric journals from Wanfang web during recent 3 years (n=61).Results Our survey showed that in the domestic geriatrics journals,the structured abstracts were used with inflexible four-heading and fixed leading words.In foreign geriatrics journals,however,non-structured abstracts were mostly applied in articles on basic research,and structured abstracts primarily appeared in clinical or survey research papers.Compared with foreign geriatrics journals,the shortages or some problems in English abstracts of the domestic geriatrics journals included a short writing,repetition of objective with title,lack of description of research background,improper description of results data,more passive voice,improper use of modal verbs.Conclusions The domestic geriatrics journals should learn the diverse forms of abstracts and content structure from foreign geriatrics journals,strengthen the elaboration of background and highlights,and use active voice in concordance with the international mainstream.
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Objective To evaluate the reporting quality of Meta-analyses published on Chinese journals of geriatrics.Methods Papers of Meta-analyses on geriatrics published in nine major Chinese journals of geriatrics before November 21,2013 were retrieved,their basic information were abstracted and evaluated through system assessment and preferred reporting items for systematic reviews and Meta-analyses (PRISMA) statement.Statistical analyses were performed with the SPSS17.0 software.Results Among the 71 internalized papers,1 was from 《Geriatrics & Health Care》,1 from 《Practical Geriatrics》,10 from 《Chinese Journal of Geriatric Care》,45 from 《Chinese Journal of Gerontology》,3 from 《Chinese Journal of Multiple Organ Diseases in the Elderly》,1 from 《Chinese Journal of Geriatric Dentistry》,5 from 《Chinese Journal of Geriatric Heart Brain and Vessel Diseases》,5 from 《Chinese Journal of Geriatrics》.55 papers (77.5％) were published in recent 3 years.The mean overall PRISMA score was(16.75±3.04)ranged from 4 to 24.The main influencing factor for the quality of Meta-analyses was the year of publication (adjusted β=-0.342,P=0.003).Conclusions The quantity and quality of Meta-analyses published on Chinese journals of geriatrics are increased and improved in recent years,but there are still some problems on the writing norms.We should promote PRISMA statement and standardize reporting format to improve the quality of Meta-analyses in the field of geriatric medicine.
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Objective To develop a scientific system of core information of health and evaluation index for the elderly Chinese people,which is suitable for the situation of our country.Methods The framework was established by extensive literature review and topic discussions.The index system was constructed with the Delphi method.Results 58 experts in different fields of health were selected in the two rounds of Delphi consultation research.The effective response rates in the two rounds were 96.88％ and 100％ respectively.The average value of the authoritative coefficient was between 0.80 and 0.96.And coefficients of variation were between 6.20 and 12.13.Based on the Delphi consultation research,the core information of health and evaluation index system for the elderly Chinese people were composed of 8 primary indicators closely associated with the positive awareness of aging and senescence and 31 other indicators.Conclusions The architecture of the core information of health and evaluation index system for the elderly Chinese people is stable,and the consultant experts tend to reach a consensus.The evaluation index system contains the most influential factors for the elderly Chinese people,and has the affirmative scientificity,applicability and feasibility.
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Objective To analyze the citation status of Chinese Journal of Geriatrics,and to evaluate the authority and quality of this journal.Methods Literatures including original research articles,short reports of original studies,reviews and clinical case reports etc.from 2003 to 2007 were collected from China national knowledge internet (CNKI) and Wanfang Database.The citation frequency,author distributions,relevant journals and foundation status were statistically analyzed.Results Totally 1649 papers were published in Chinese Journal of Geriatrics from 2003 to 2007,among which 1280 papers were cited 9062 times by 946 kinds of journals,the average citation times was 7.08 times,and the top citation times was 131 times.270 articles were cited 10 or more times (21.09％).The top 3 relevant journals with high citations from Chinese Journal of Geriatrics were Chinese Journal of Gerontology,Chinese Journal of Geriatrics and Chinese Journal of Misdiagnostics (totally 591 times,6.52％).The self-citation rate was 1.95％.445 articles were supported by different kinds of funds (totally 112 kinds),and majority of articles were supported by National Natural Science Foundation of China.Articles supported by 106 kinds of funds were cited and the total citation times was 2312 times.Conclusions Literatures in Chinese Journal of Geriatrics have high quality and authority with an amount of readers and relatively stable relevant journals.Journal quality and academic level are highly improved,but further efforts are needed to promote the coordinated development of regions.
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Objective To analyze the citation of papers published in Chinese Journal of Geriatrics from the year 2008 to 2012,and evaluate the quality and academic level of the journal.Methods Based on the information from Wanfang database,bibliometric analysis was conducted to analyze number of cited papers,citation frequency,citation time distribution,authors,funds supports etc,and immediacy index and citation half-life were calculated.Results A total of 1567 papers were published in the journal from the year 2008 to 2012,and 377 articles were cited for 669 times with citation rate of 24.06％.The average number of cited times was 1.77,and the top value per article cited was 18 times.There were 12 authors whose articles were cited 6 and over times,and 11 affiliations whose articles were cited more than 10 times.Among 377 papers,105 papers (27.85％) were supported by funds,among which the majority was provincial fund (36 papers) and national fund (35 papers).Immediacy index from the year 2008 to 2012 were 0.042,0.032,0.019,0.067 and 0.006,respectively,and the citation half-life was 1.71 in the year 2012.Conclusions Articles published in Chinese Journal of Geriatrics have high-quality and can reflect the development and research progress in geriatric medicine.The journal is one of the most important information resources in geriatric academic field in China.
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Objective To investigate the characteristics of the author groups in 《Chinese Journal of Geriatrics》,in order to provide references for the future construction and development of the author ranks.Methods Bibliometric method was used to analyze the quantity of papers,region distributions,core authors and cooperative rate in 《Chinese Journal of Geriatrics》 from 2009 to 2013.Results The total amount of papers published in 《Chinese Journal of Geriatrics》》 from 2009 to 2013 was 1636,involving 31 provinces,autonomous regions,municipalities and administrative region.Among these,Beijing,Zhejiang,Tianjin and Jiangsu were the 3 top contributing regions,accounting for 54.0 percent (884/1636 papers).The 1636 papers were contributed by 1435 authors (first authors),of whom 1275 authors published only one paper,accounting for 87.7％ (1275/1435),and their papers accounted for 77.9％ of the total published papers (1275 /1636).27 authors had high yield of 3 or more papers published and deep influence,and they published 95 papers (5.8％).The degree of cooperation was 4.6 (7599 /1636),and the cooperation rate was 93.8％ (1534/1636) within the five years.Conclusions 《Chinese Journal of Geriatrics》is quite influential and attractive in the fields of geriatrics,and a good cooperative relationship is displayed between different authors and authors' institutions.